Smurf1-IN-1
Smurf1-IN-1 is a potent and selective SMURF1 inhibitor with an oral IC50 of 92 nM. It has shown significant in vivo efficacy in a rat pulmonary hypertension model, making it a valuable chemical probe for studying ubiquitination pathways in cardiovascular and fibrotic diseases.
Product Specifications
CAS Number
1824708-03-3
Field of Research
Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
O=C (C1=C (C) N (C2=CC=C (C3CC3) C=C2Cl) N=N1) NC4=C (C) N (C) N (C5CCCCC5) C4=O
Molecular Formula
C24H29ClN6O2
Molecular Weight
468.98
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-5315R-RBITC 100 µL
Phospho-EGFR (Tyr1092) Polyclonal Antibody, RBITC Conjugated
Sign In for Pricing
View Details 
bs-3899R-RBITC 100 µL
CYP24A1 Polyclonal Antibody, RBITC Conjugated
Sign In for Pricing
View Details 
MBS2104387-01 5x 96 Tests
Human CD27 Binding Protein (CD27BP) Antibody Pair Kit (with Standard)
Sign In for Pricing
View Details MBS2104387-02 5x 96 Tests + MBS2090685 (Ab Pairs Support Pack 1,5x 96 Tests)
Human CD27 Binding Protein (CD27BP) Antibody Pair Kit (with Standard)
Sign In for Pricing
View Details