Smurf1-IN-1
Smurf1-IN-1 is a potent and selective SMURF1 inhibitor with an oral IC50 of 92 nM. It has shown significant in vivo efficacy in a rat pulmonary hypertension model, making it a valuable chemical probe for studying ubiquitination pathways in cardiovascular and fibrotic diseases.
Product Specifications
CAS Number
1824708-03-3
Field of Research
Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
O=C (C1=C (C) N (C2=CC=C (C3CC3) C=C2Cl) N=N1) NC4=C (C) N (C) N (C5CCCCC5) C4=O
Molecular Formula
C24H29ClN6O2
Molecular Weight
468.98
Storage Conditions
-20°C
Notes
For research use only.
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