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Smurf1-IN-1

Smurf1-IN-1 is a potent and selective SMURF1 inhibitor with an oral IC50 of 92 nM. It has shown significant in vivo efficacy in a rat pulmonary hypertension model, making it a valuable chemical probe for studying ubiquitination pathways in cardiovascular and fibrotic diseases.

Product Specifications

CAS Number

1824708-03-3

Field of Research

Protein Biochemistry, Stem Cell & Developmental Biology

Smiles

O=C (C1=C (C) N (C2=CC=C (C3CC3) C=C2Cl) N=N1) NC4=C (C) N (C) N (C5CCCCC5) C4=O

Molecular Formula

C24H29ClN6O2

Molecular Weight

468.98

Storage Conditions

-20°C

Notes

For research use only.

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