Apicidin
Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiproliferative and antiparasitic properties. It has been shown to reduce amyloid-beta load and improve memory in APP/PS1 mouse models of Alzheimer's disease, while also inducing apoptosis and autophagy in leukemia cell research.
Product Specifications
CAS Number
183506-66-3
Product Name Alternative
OSI 2040, OSI2040, OSI-2040, HDAC, Autophagy, Apoptosis, Apicidin
Field of Research
Cell Biology, Epigenetics & Chromatin, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
HDAC inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 1 mg/ml)
Smiles
[H][C@]12CCCCN1C (=O) [C@@] ([H]) (NC (=O) [C@H] (Cc1cn (OC) c3ccccc13) NC (=O) [C@H] (CCCCCC (=O) CC) NC2=O) [C@@H] (C) CC
Molecular Formula
C34H49N5O6
Molecular Weight
623.78
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Cyclo[ (2S) -2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl- (2R) -2-piperidinexcarbonyl]
Available Sizes
Frequently Asked Questions
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