TSPO ligand-3
TSPO ligand-3 is an AUTAC2-based bifunctional molecule containing p-fluorobenzylguanine (FBnG) and a synthetic FKBP ligand (SLF) . It potently inhibits FKBP12 in cellular models like HeLa cells and serves as a key tool for studying targeted protein degradation and autophagy-tethering compound mechanisms in vitro.
Product Specifications
CAS Number
2241669-89-4
Field of Research
Pharmacology & Drug Discovery
Smiles
[C@@H] (OC (=O) C1N (C (C (C (CC) (C) C) =O) =O) CCCC1) (CCC2=CC (OC) =C (OC) C=C2) C3=CC (NC (CCC (O) =O) =O) =CC=C3
Molecular Formula
C34H44N2O9
Molecular Weight
624.72
Storage Conditions
-20°C
Notes
For research use only.
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