TMX-4153
TMX-4153 is a bivalent PROTAC molecule that selectively recruits the VHL E3 ligase to degrade endogenous PIP4K2C with a K D of 42 nM. This tool compound is applicable for studying PIP4K2C biology in cellular and biochemical assays.
Product Specifications
CAS Number
2867519-91-1
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C1C2 (CCN1C=3C=C (NC=4N=C (C (Cl) =CN4) C5=CC (=CC=C5) C6=CC=CC=C6) C=NC3) CCN (C (CCCCCC (N[C@H] (C (=O) N7[C@H] (C (N[C@@H] (C) C8=CC=C (C=C8) C9=C (C) N=CS9) =O) C[C@@H] (O) C7) [C@] (C) (C) C) =O) =O) CC2
Molecular Formula
C59H67ClN10O6S
Molecular Weight
1079.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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