SH491
SH491 (Compound 33) is a potent small-molecule inhibitor of RANKL-induced osteoclast differentiation (IC50 = 11.8 nM in BMMs) and downregulates key osteoclastogenic markers like TRAP and CTSK. It is a valuable research tool for studying bone resorption mechanisms in osteoporosis models, applicable in both cellular and in vivo experimental systems.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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