Rezatapopt
Rezatapopt (PC14586) is a selective small molecule reactivator of the p53 Y220C mutant, restoring its wild-type conformation and transcriptional function. This compound is utilized in preclinical research for studying locally advanced or metastatic solid tumors, with demonstrated activity in both in vitro and in vivo models.
Product Specifications
CAS Number
2636846-41-6
Product Name Alternative
P53, PC14586
Field of Research
Cell Biology
Purity
98.12% (May vary between batches)
Solubility
DMSO:80 mg/mL (146.64 mM)
Smiles
N (C1=C2C (N (CC (F) (F) F) C (C#CCNC3=C (OC) C=C (C (NC) =O) C=C3) =C2) =CC=C1) [C@H]4[C@@H] (F) CN (C) CC4
Molecular Formula
C28H31F4N5O2
Molecular Weight
545.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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