YS-363
YS-363 is a potent, selective, and orally bioavailable EGFR inhibitor with IC50 values of 0.96 nM (wild-type) and 0.67 nM (L858R mutant) . It induces G0/G1 cell cycle arrest and apoptosis in vitro and has demonstrated antitumor efficacy in vivo, making it a valuable tool for oncology research targeting EGFR-driven cancers.
Product Specifications
CAS Number
2470908-90-6
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N=1C=NC (=C2C=C (OCCCN3CCOCC3) C (OC) =CC12) C=4C=5C=CC=CC5NC4C=6C=CC=CC6
Molecular Formula
C30H30N4O3
Molecular Weight
494.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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