XY-52
Compound 32 (XY-52) is a small molecule ST2 inhibitor with IC50 values of 5.68 μM (AlphaLISA) and 4.59 μM (HEK-Blue) . In a GVHD mouse model, it promotes proinflammatory T-cell proliferation and reduces plasma sST2 and IFNγ levels, supporting its use in immunology and inflammation research.
Product Specifications
Field of Research
Immunology & Inflammation
Smiles
CC1=CC ([N+] ([O-]) =O) =CC=C1C2=CC=C (CN3C (C4=CC=CC (N5CC (CC6) NC6C5) =C4) CCC3) N2CC
Molecular Formula
C30H37N5O2
Molecular Weight
499.65
Storage Conditions
-20°C
Notes
For research use only.
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