WRN inhibitor 5
WRN Inhibitor 5 (Example 157) is a cyclic vinyl sulfone compound that acts as a potent and selective inhibitor of the Werner syndrome helicase (WRN) . This tool compound is used in cancer research to study synthetic lethal targeting of microsatellite unstable (MSI) cancers in both in vitro and in vivo models.
Product Specifications
CAS Number
2923009-95-2
Field of Research
Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Smiles
O (CC1=CC=CC=C1) C2=C (C=CC=C2) C3=C (O) C=C (C (N[C@@H]4C=CS (=O) (=O) C4) =O) C (=O) N3
Molecular Formula
C23H20N2O6S
Molecular Weight
452.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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