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WRN inhibitor 3

WRN Inhibitor 3 (example 110) is a cyclic vinyl sulfone compound that acts as a potent and selective inhibitor of the Werner syndrome helicase (WRN) . This tool compound is used in cancer research to study synthetic lethal approaches in microsatellite unstable (MSI) cancers, both in vitro and in vivo.

Product Specifications

CAS Number

2923009-48-5

Field of Research

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Smiles

O (CC1CC1) C2=C (C=CC=C2) C=3NC (=O) C (C (N[C@H]4CS (=O) (=O) C=C4) =O) =CC3

Molecular Formula

C20H20N2O5S

Molecular Weight

400.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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