VRT-534
VRT-534 is a selective connexin 26 (Cx26) modulator, binding with higher potency to the K188N mutant (EC50 5 μM) than to wild-type (EC50 19 μM) . It is a valuable research tool for investigating connexin function in models of hearing loss, applicable in both in vitro and in vivo studies.
Product Specifications
CAS Number
926664-32-6
Field of Research
Signal Transduction
Smiles
C (NC=1SC ([C@H] (C2=C (Cl) C=CC=C2) N3C[C@H] (O) CC3) =CN1) (=O) C4 (CC4) C=5C=C6C (=CC5) OCO6
Molecular Formula
C25H24ClN3O4S
Molecular Weight
497.99
Storage Conditions
-20°C
Notes
For research use only.
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