SCAL-266
SCAL-266 is a potent mitochondrial complex I inhibitor (IC50 = 0.83 μM) that disrupts oxidative phosphorylation, reducing OCR and MMP while increasing ROS. Its antiproliferative effects make it a valuable research tool for studying OXPHOS-dependent cancers in vitro and exploring metabolic vulnerabilities in cellular models.
Product Specifications
CAS Number
2798953-78-1
Field of Research
Cell Biology, Metabolism Research
Smiles
C (C=1C=C (C=CC1) N2CCN (C (=O) C3CC3) CC2) N4N=C (C (NC5=CC=C (C (F) (F) F) C=C5) =O) C=C4C
Molecular Formula
C27H28F3N5O2
Molecular Weight
511.54
Storage Conditions
-20°C
Notes
For research use only.
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