(S, R, S) -AHPC-Me-C5-COOH

[2229976-21-8]

12352005

H302, H315, H319, H335

E3 Ligase Ligand-Linker Conjugates

Reference compound

PROTAC

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/s-r-s-ahpc-me-c5-cooh.html

96.87

DMSO : 100 mg/mL (ultrasonic)

O=C(N[C@H](C1=CC=C(C2=C(C)N=CS2)C=C1)C)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCC(O)=O)=O)=O)C[C@H](O)C3

C30H42N4O6S

586.74

H302, H315, H319, H335

[1]Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25 (12) :1938-1947.

Room Temperature

4°C (Powder, sealed storage, away from moisture)

Reference compound1

No Development Reported

Von Hippel-Lindau (VHL)