SWS1
SWS1 is a potent, biotin-conjugated PD-L1 inhibitor with an IC50 of 1.8 nM. It promotes anti-tumor immunity by enhancing tumor-infiltrating lymphocytes, demonstrating significant in vivo efficacy with 66.1% tumor growth inhibition in a B16-F10 melanoma model.
Product Specifications
CAS Number
2922115-32-8
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience
Smiles
C (CCCC (NCCNC (=O) C1N (CC2=C (OCC3=CC (C#N) =CC=C3) C=C (OCC4=C (C) C (=CC=C4) C5=CC=CC=C5) C (Cl) =C2) CCCC1) =O) [C@H]6[C@@]7 ([C@] (CS6) (NC (=O) N7) [H]) [H]
Molecular Formula
C47H53ClN6O5S
Molecular Weight
849.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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