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PARP1-IN-14

PARP1-IN-14 (compound 19k) is a highly potent PARP1 inhibitor with an IC50 of 0.6 nM. It exhibits strong antiproliferative activity in BRCA-deficient cell lines such as MDA-MB-436 and Capan-1. This inhibitor is a valuable chemical probe for studying DNA damage response and synthetic lethality in cancer research models.

Product Specifications

CAS Number

2098639-70-2

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Smiles

CC1N2C (=NN=C2CN (C (=O) C3=CC (CC=4C=5C (C (=O) NN4) =CC=CC5) =CC=C3F) C1) C=6N=C (OC) C=CC6

Molecular Formula

C28H24FN7O3

Molecular Weight

525.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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