PARP1-IN-14
PARP1-IN-14 (compound 19k) is a highly potent PARP1 inhibitor with an IC50 of 0.6 nM. It exhibits strong antiproliferative activity in BRCA-deficient cell lines such as MDA-MB-436 and Capan-1. This inhibitor is a valuable chemical probe for studying DNA damage response and synthetic lethality in cancer research models.
Product Specifications
CAS Number
2098639-70-2
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
CC1N2C (=NN=C2CN (C (=O) C3=CC (CC=4C=5C (C (=O) NN4) =CC=CC5) =CC=C3F) C1) C=6N=C (OC) C=CC6
Molecular Formula
C28H24FN7O3
Molecular Weight
525.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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