Lepadin E
Lepadin E is a cytotoxic small molecule that induces ferroptosis by activating the p53-SLC7A11-GPX4 axis, leading to increased ROS, lipid peroxidation, and ACSL4 expression. Its potent antitumor activity makes it a valuable tool for studying ferroptosis mechanisms in cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
444914-19-6
Field of Research
Cell Biology, Metabolism Research
Smiles
C (CCC[C@@H] (CCC) O) [C@@H]1[C@]2 ([C@] (N[C@@H] (C) [C@H] (OC (/C=C/CCCCC) =O) C2) (CCC1) [H]) [H]
Molecular Formula
C26H47NO3
Molecular Weight
421.66
Storage Conditions
-20°C
Notes
For research use only.
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