STAT3-IN-20
STAT3-IN-20 is a selective STAT3 SH2 domain inhibitor (IC50 = 0.65 μM) that blocks STAT3 activation and downstream signaling. It exhibits antiproliferative activity, induces cell cycle arrest and apoptosis in cancer cell lines like DU145 and MDA-MB-231, making it a useful probe for studying STAT3-driven cancers in vitro.
Product Specifications
CAS Number
2768427-54-7
Field of Research
Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (C=1C=C2C (N (C (=N2) C3=CC=C (F) C=C3) C4CC4) =CC1N5CCN (C) CC5) C=6SC (=NN6) C7=CC=C (C (F) (F) F) C=C7
Molecular Formula
C30H27F4N7S
Molecular Weight
593.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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