Anti-inflammatory agent 56
Anti-inflammatory agent 56 (Compound 9) is a selective COX-2 inhibitor (IC50 = 0.54 μM) with antioxidant properties. It mitigates oxidative stress and neuroinflammation by suppressing Keap1, COX-2, and iNOS, as demonstrated in cellular models. Its low acute toxicity (LD50 >1000 mg/kg in mice) supports its use in preclinical inflammation and neurodegeneration research.
Product Specifications
CAS Number
2413127-32-7
Field of Research
Immunology & Inflammation, Neuroscience
Smiles
OC1=C (C=2N (N=C (N2) C3=C (O) C=C (C (F) (F) F) C=C3) C4=CC=C (S (N) (=O) =O) C=C4) C=CC=C1
Molecular Formula
C21H15F3N4O4S
Molecular Weight
476.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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