NF-κB-IN-11
NF-κB-IN-11 is a potent small molecule inhibitor that suppresses TNF-α-induced NF-κB activation and nuclear translocation by reducing phospho-IKK, IκBα, and p65 levels. It demonstrates anti-inflammatory efficacy in a DSS-induced mouse colitis model and shows a high oral MTD (>1852 mg/kg), supporting its use in inflammatory disease research.
Product Specifications
CAS Number
2768833-35-6
Field of Research
Signal Transduction
Smiles
C (OC) (=O) C=1C2C (C#CC3=CC=C (C) C=C3) CC (O2) C1C (OC) =O
Molecular Formula
C19H18O5
Molecular Weight
326.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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