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EGFR-IN-88

EGFR-IN-88 (Compound 4i) is a potent EGFR inhibitor with an IC50 of 87 nM. It demonstrates cytotoxic activity against A549 lung cancer cells with an IC50 of 3.902 μM and can induce apoptosis, making it a useful tool for in vitro cancer research and kinase signaling studies.

Product Specifications

CAS Number

2944452-34-8

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

C (C) C1=NC2=C (N=C1CC) C=CC (=C2) C=3OC (SCC (=O) C4=C (Cl) C=C (Cl) C=C4) =NN3

Molecular Formula

C22H18Cl2N4O2S

Molecular Weight

473.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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