EGFR-IN-88
EGFR-IN-88 (Compound 4i) is a potent EGFR inhibitor with an IC50 of 87 nM. It demonstrates cytotoxic activity against A549 lung cancer cells with an IC50 of 3.902 μM and can induce apoptosis, making it a useful tool for in vitro cancer research and kinase signaling studies.
Product Specifications
CAS Number
2944452-34-8
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (C) C1=NC2=C (N=C1CC) C=CC (=C2) C=3OC (SCC (=O) C4=C (Cl) C=C (Cl) C=C4) =NN3
Molecular Formula
C22H18Cl2N4O2S
Molecular Weight
473.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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