NLRP3-IN-19
JT001 (NLRP3-IN-19) is an orally bioavailable, selective NLRP3 inflammasome inhibitor that blocks its assembly, thereby inhibiting IL-1β release and pyroptosis. It is a valuable research tool for studying NLRP3-driven pathologies, including nonalcoholic steatohepatitis (NASH) and liver fibrosis, in both cellular and animal models.
Product Specifications
CAS Number
2238819-65-1
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
N (C (NS (=O) (=O) C1=C2N (N=C1) CCCO2) =O) C3=C4C (=CC5=C3CCC5) CCC4
Molecular Formula
C19H22N4O4S
Molecular Weight
402.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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