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NLRP3-IN-20

NLRP3-IN-20 is a potent and orally bioavailable NLRP3 inflammasome inhibitor, demonstrating an IC50 of 25 nM against IL-1β release. It has shown significant therapeutic efficacy in preclinical models of inflammatory diseases, including non-alcoholic steatohepatitis, septic shock, and colitis.

Product Specifications

CAS Number

2428478-22-0

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

O=C (NC=1C2=C (C=C3C1CCC3) CCC2) NS (=O) (=O) C4=CC=C (C=C4) CN (C) C

Molecular Formula

C22H27N3O3S

Molecular Weight

413.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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