NLRP3-IN-20
NLRP3-IN-20 is a potent and orally bioavailable NLRP3 inflammasome inhibitor, demonstrating an IC50 of 25 nM against IL-1β release. It has shown significant therapeutic efficacy in preclinical models of inflammatory diseases, including non-alcoholic steatohepatitis, septic shock, and colitis.
Product Specifications
CAS Number
2428478-22-0
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O=C (NC=1C2=C (C=C3C1CCC3) CCC2) NS (=O) (=O) C4=CC=C (C=C4) CN (C) C
Molecular Formula
C22H27N3O3S
Molecular Weight
413.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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