LRRK2-IN-10
LRRK2-IN-10 is a potent and brain-penetrant inhibitor that selectively targets the G2019S mutant of LRRK2 kinase, demonstrating IC50 values of 11 nM and 5.2 nM against key phosphorylation sites. This compound is a valuable research tool for investigating the pathogenesis of Parkinson's disease in both cellular and animal models.
Product Specifications
CAS Number
2704562-80-9
Field of Research
Cell Biology
Smiles
N (C=1C=C2C (=NNC2=CC1) C=3C=NOC3) [C@@H]4C=5C (CC4) =CC (C#N) =CC5
Molecular Formula
C20H15N5O
Molecular Weight
341.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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