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LRRK2-IN-10

LRRK2-IN-10 is a potent and brain-penetrant inhibitor that selectively targets the G2019S mutant of LRRK2 kinase, demonstrating IC50 values of 11 nM and 5.2 nM against key phosphorylation sites. This compound is a valuable research tool for investigating the pathogenesis of Parkinson's disease in both cellular and animal models.

Product Specifications

CAS Number

2704562-80-9

Field of Research

Cell Biology

Smiles

N (C=1C=C2C (=NNC2=CC1) C=3C=NOC3) [C@@H]4C=5C (CC4) =CC (C#N) =CC5

Molecular Formula

C20H15N5O

Molecular Weight

341.37

Storage Conditions

-20°C

Notes

For research use only.

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