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Thalidomide-NH- (CH2) 2-NH2 TFA

Thalidomide-NH- (CH2) 2-NH2 TFA is a key alkyl-modified Cereblon (CRBN) ligand for constructing PROTAC degraders. It serves as a pivotal intermediate in synthesizing heterobifunctional molecules, such as those targeting SHP2, for targeted protein degradation research in both cellular and in vivo models.

Product Specifications

CAS Number

1957235-67-4

Field of Research

Cell Biology, Immunology & Inflammation; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Smiles

NCCNC1=C2C (=O) N (C3C (=O) NC (=O) CC3) C (=O) C2=CC=C1.OC (=O) C (F) (F) F

Molecular Formula

C17H17F3N4O6

Molecular Weight

430.34

Storage Conditions

-20°C

Notes

For research use only.

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