MY-673

MY-673 is a colchicine-binding site inhibitor that suppresses tubulin polymerization and disrupts ERK signaling, leading to modulation of SMAD4 in the TGF-β pathway. This mechanism results in potent anti-proliferative, anti-migratory, and pro-apoptotic effects validated in both cellular and animal models, supporting its use in oncology and cytoskeleton research.