HDAC-IN-63
HDAC-IN-63 is a potent dual FLT3 and HDAC1 inhibitor with sub-nanomolar and low-nanomolar IC50 values, respectively. It demonstrates anti-leukemic activity in vitro by inhibiting proliferation, inducing apoptosis, and causing cell cycle arrest in MV4-11 AML cells, making it a valuable tool for acute myeloid leukemia research.
Product Specifications
CAS Number
2920046-95-1
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
C (N1C=2C (N=C1) =CC=C (C2) C3=CC (NC (CCCCCCC (NO) =O) =O) =NN3) C4=C (Cl) C=CC=C4Cl
Molecular Formula
C25H26Cl2N6O3
Molecular Weight
529.42
Storage Conditions
-20°C
Notes
For research use only.
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