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TWIK-1/TREK-1-IN-1

TWIK-1/TREK-1-IN-3 is a selective inhibitor of TREK-1 homodimers and TWIK-1/TREK-1 heterodimers, key antidepressant targets within the K2P channel family. With IC50 values of 9.36 μM and 14.6 μM respectively, it exhibits antidepressant-like effects in preclinical research, supporting its use in neuropharmacology and depression-related in vitro and in vivo studies.

Product Specifications

CAS Number

1440532-30-8

Field of Research

Neuroscience; Cell Biology, Pharmacology & Drug Discovery

Smiles

OC1 (CCN (C[C@H] (COC2=CC=C (C (F) (F) F) C=C2) O) CC1) C3=CC=CC=C3

Molecular Formula

C21H24F3NO3

Molecular Weight

395.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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