TWIK-1/TREK-1-IN-1
TWIK-1/TREK-1-IN-3 is a selective inhibitor of TREK-1 homodimers and TWIK-1/TREK-1 heterodimers, key antidepressant targets within the K2P channel family. With IC50 values of 9.36 μM and 14.6 μM respectively, it exhibits antidepressant-like effects in preclinical research, supporting its use in neuropharmacology and depression-related in vitro and in vivo studies.
Product Specifications
CAS Number
1440532-30-8
Field of Research
Neuroscience; Cell Biology, Pharmacology & Drug Discovery
Smiles
OC1 (CCN (C[C@H] (COC2=CC=C (C (F) (F) F) C=C2) O) CC1) C3=CC=CC=C3
Molecular Formula
C21H24F3NO3
Molecular Weight
395.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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