TWIK-1/TREK-1-IN-2
TWIK-1/TREK-1-IN-2 (Compound 2g) is a dual inhibitor of the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 values of 10.13 μM and 15.5 μM, respectively. This small molecule exhibits antidepressant-like effects in preclinical studies, making it a useful research tool for investigating potassium channel function in neurological and psychiatric disorders.
Product Specifications
CAS Number
1440532-32-0
Field of Research
Neuroscience; Cell Biology, Pharmacology & Drug Discovery
Smiles
C ([C@@H] (COC1=CC=C (C (F) (F) F) C=C1) O) N2CCC (CC2) N3CCCCC3
Molecular Formula
C20H29F3N2O2
Molecular Weight
386.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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