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TWIK-1/TREK-1-IN-2

TWIK-1/TREK-1-IN-2 (Compound 2g) is a dual inhibitor of the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 values of 10.13 μM and 15.5 μM, respectively. This small molecule exhibits antidepressant-like effects in preclinical studies, making it a useful research tool for investigating potassium channel function in neurological and psychiatric disorders.

Product Specifications

CAS Number

1440532-32-0

Field of Research

Neuroscience; Cell Biology, Pharmacology & Drug Discovery

Smiles

C ([C@@H] (COC1=CC=C (C (F) (F) F) C=C1) O) N2CCC (CC2) N3CCCCC3

Molecular Formula

C20H29F3N2O2

Molecular Weight

386.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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