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TWIK-1/TREK-1-IN-3

TWIK-1/TREK-1-IN-3 is a selective small-molecule inhibitor targeting the TREK-1 potassium channel and its heterodimers with TWIK-1. It demonstrates antidepressant-like effects in preclinical models, making it a valuable pharmacological tool for studying depression-related neurobiology and K2P channel function in both cellular and animal systems.

Product Specifications

CAS Number

1440532-33-1

Product Name Alternative

PotassiumChannel, Potassium Channel, TREK-1

Field of Research

Neuroscience; Cell Biology, Pharmacology & Drug Discovery

Purity

99.04% (May vary between batches)

Solubility

DMSO:20 mg/mL (53.7 mM)

Smiles

C ([C@@H] (COC1=CC=C (C (F) (F) F) C=C1) O) N2CCC (CC2) N3CCCC3

Molecular Formula

C19H27F3N2O2

Molecular Weight

372.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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