TWIK-1/TREK-1-IN-3
TWIK-1/TREK-1-IN-3 is a selective small-molecule inhibitor targeting the TREK-1 potassium channel and its heterodimers with TWIK-1. It demonstrates antidepressant-like effects in preclinical models, making it a valuable pharmacological tool for studying depression-related neurobiology and K2P channel function in both cellular and animal systems.
Product Specifications
CAS Number
1440532-33-1
Product Name Alternative
PotassiumChannel, Potassium Channel, TREK-1
Field of Research
Neuroscience; Cell Biology, Pharmacology & Drug Discovery
Purity
99.04% (May vary between batches)
Solubility
DMSO:20 mg/mL (53.7 mM)
Smiles
C ([C@@H] (COC1=CC=C (C (F) (F) F) C=C1) O) N2CCC (CC2) N3CCCC3
Molecular Formula
C19H27F3N2O2
Molecular Weight
372.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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