CDK/HDAC-IN-3
CDK/HDAC-IN-3 is an orally bioavailable, dual inhibitor targeting CDK9/12/13 and HDAC1/2/3 with IC50 values ranging from 62.12 to 100 nM. It demonstrates research utility in acute myeloid leukemia (AML), showing potential for both in vitro cellular studies and in vivo efficacy models in oncology research.
Product Specifications
CAS Number
2944087-54-9
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
N (C (=O) C1=C (Cl) C=CC=C1Cl) C=2C (C (NC3=CC=C (C (NC4=C (N) C=CC=C4) =O) C=C3) =O) =NNC2
Molecular Formula
C24H18Cl2N6O3
Molecular Weight
509.34
Storage Conditions
-20°C
Notes
For research use only.
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