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CDK/HDAC-IN-3

CDK/HDAC-IN-3 is an orally bioavailable, dual inhibitor targeting CDK9/12/13 and HDAC1/2/3 with IC50 values ranging from 62.12 to 100 nM. It demonstrates research utility in acute myeloid leukemia (AML), showing potential for both in vitro cellular studies and in vivo efficacy models in oncology research.

Product Specifications

CAS Number

2944087-54-9

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Smiles

N (C (=O) C1=C (Cl) C=CC=C1Cl) C=2C (C (NC3=CC=C (C (NC4=C (N) C=CC=C4) =O) C=C3) =O) =NNC2

Molecular Formula

C24H18Cl2N6O3

Molecular Weight

509.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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