MAT2A-IN-10
MAT2A-IN-10 (Compound 28) is a potent, orally bioavailable MAT2A inhibitor with an IC50 of 26 nM. It is a valuable chemical probe for cancer research, particularly in studying methionine metabolism and its role in MTAP-deleted cancers in both cellular and animal models.
Product Specifications
CAS Number
2924825-23-8
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
O=C1N (C=2C (C (=O) N1C=3C=C4N5C (=NC4=CC3) CN (C) CC5) =CC=C (OCC) N2) C6=CC=C (OC (F) F) C=C6
Molecular Formula
C27H24F2N6O4
Molecular Weight
534.51
Storage Conditions
-20°C
Notes
For research use only.
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