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MAT2A-IN-10

MAT2A-IN-10 (Compound 28) is a potent, orally bioavailable MAT2A inhibitor with an IC50 of 26 nM. It is a valuable chemical probe for cancer research, particularly in studying methionine metabolism and its role in MTAP-deleted cancers in both cellular and animal models.

Product Specifications

CAS Number

2924825-23-8

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

O=C1N (C=2C (C (=O) N1C=3C=C4N5C (=NC4=CC3) CN (C) CC5) =CC=C (OCC) N2) C6=CC=C (OC (F) F) C=C6

Molecular Formula

C27H24F2N6O4

Molecular Weight

534.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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