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HIV-1 protease-IN-8

HIV-1 protease-IN-8 (compound 34b) is a highly potent HIV-1 protease inhibitor with an IC50 of 0.32 nM. It shows robust antiviral activity against both wild-type (IC50=0.29 μM, HIV-1 NL4-3) and multidrug-resistant (IC50=1.90 μM, HIV-1 MDR) viral strains, making it a valuable tool for in vitro antiviral mechanism and resistance studies.

Product Specifications

CAS Number

2925287-55-2

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Smiles

N (S (=O) (=O) C1=CC=C (O) C=C1) (C[C@H] ([C@H] (CC2=CC=CC=C2) NC (=O) [C@@H]3CCNC3) O) CC (C) C

Molecular Formula

C25H35N3O5S

Molecular Weight

489.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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