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ATR-IN-23

ATR-IN-23 (Compound 34) is a highly potent and selective ATR inhibitor with an IC50 of 1.5 nM. It demonstrates antiproliferative activity in LoVo cells and synthetic lethality in HT-29 cells, supporting its use as a research tool for investigating DNA damage response pathways and associated cancer models in vitro.

Product Specifications

CAS Number

2923800-62-6

Field of Research

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Smiles

N (C) C=1N (C2=NC (=C3C (=N2) C (S (C) (=O) =O) =CS3) N4[C@H] (C) COCC4) C=5C (N1) =CC=CC5

Molecular Formula

C20H22N6O3S2

Molecular Weight

458.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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