ATR-IN-23
ATR-IN-23 (Compound 34) is a highly potent and selective ATR inhibitor with an IC50 of 1.5 nM. It demonstrates antiproliferative activity in LoVo cells and synthetic lethality in HT-29 cells, supporting its use as a research tool for investigating DNA damage response pathways and associated cancer models in vitro.
Product Specifications
CAS Number
2923800-62-6
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
N (C) C=1N (C2=NC (=C3C (=N2) C (S (C) (=O) =O) =CS3) N4[C@H] (C) COCC4) C=5C (N1) =CC=CC5
Molecular Formula
C20H22N6O3S2
Molecular Weight
458.56
Storage Conditions
-20°C
Notes
For research use only.
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