SLMP53-2
SLMP53-2 is a small molecule reactivator of the mutant p53-Y220C. It restores wild-type conformation and transcriptional function by enhancing Hsp70 interaction, leading to cell cycle arrest, apoptosis, and ER stress in vitro, demonstrating potential for cancer research.
Product Specifications
CAS Number
1826116-38-4
Field of Research
Cell Biology
Smiles
C ([C@@H]1N2[C@@] (C=3C (C2=O) =CC=CC3) (OC1) C4=CC=CC=C4) C=5C=6C (N (C) C5) =CC=CC6
Molecular Formula
C26H22N2O2
Molecular Weight
394.47
Storage Conditions
-20°C
Notes
For research use only.
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