Enpp-1-IN-17
Enpp-1-IN-17 is a selective ENPP1 inhibitor with a Ki of 100 nM-1 μM against cGAMP hydrolysis and >1 μM for ATP, showing >6.4-fold selectivity. This compound is a valuable research tool for studying the cGAS-STING pathway in cancer immunotherapy and inflammatory disease models, both in vitro and in vivo.
Product Specifications
CAS Number
2289736-54-3
Field of Research
Metabolism Research
Smiles
O (C) C1=CC=2C (=NC=NC2C=C1OC) N3CCC4 (CC3) CCNC4
Molecular Formula
C18H24N4O2
Molecular Weight
328.41
Storage Conditions
-20°C
Notes
For research use only.
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