COX-2-IN-32
COX-2-IN-32 (2f) is a dual iNOS/COX-2 inhibitor that suppresses NF-κB signaling. It exhibits anti-inflammatory activity by inhibiting nitric oxide production in LPS-stimulated RAW264.7 macrophages with an IC50 of 11.2 μM, making it a useful research tool for studying inflammation in cellular models.
Product Specifications
CAS Number
2725863-08-9
Field of Research
Immunology & Inflammation, Neuroscience, Signal Transduction
Purity
98.11% (May vary between batches)
Smiles
C (/C=C/C1=CC=C (OC2=CC=C (OC) C=C2) C=C1) (=O) C3=CC (OC) =C (OC) C (OC) =C3
Molecular Formula
C25H24O6
Molecular Weight
420.45
Storage Conditions
-20°C
Notes
For research use only.
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