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TLR8 agonist 6

This potent small molecule TLR8 agonist demonstrates high activity in vitro, with EC50 values of 0.052 μM for TLR8 activation and 0.031 μM for IL-12p40 induction in human PBMCs. It is a valuable research tool for studying immunology in contexts including antiviral responses, autoimmunity, and cancer, both in vitro and in animal models.

Product Specifications

CAS Number

2616605-55-9

Field of Research

Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery

Smiles

N ([C@@] (CNC (C) =O) (CCCC) C) C=1C2=C (C=C (C (N (C) C) =O) C=N2) N=C (N) N1

Molecular Formula

C19H29N7O2

Molecular Weight

387.48

Storage Conditions

-20°C

Notes

For research use only.

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