TLR8 agonist 6
This potent small molecule TLR8 agonist demonstrates high activity in vitro, with EC50 values of 0.052 μM for TLR8 activation and 0.031 μM for IL-12p40 induction in human PBMCs. It is a valuable research tool for studying immunology in contexts including antiviral responses, autoimmunity, and cancer, both in vitro and in animal models.
Product Specifications
CAS Number
2616605-55-9
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery
Smiles
N ([C@@] (CNC (C) =O) (CCCC) C) C=1C2=C (C=C (C (N (C) C) =O) C=N2) N=C (N) N1
Molecular Formula
C19H29N7O2
Molecular Weight
387.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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