Pimicotinib
Pimicotinib (ABSK021) is a highly selective and potent CSF1R inhibitor used in preclinical research. It demonstrates antitumor activity in models of advanced solid tumors, including tenosynovial giant cell tumor, by targeting tumor-associated macrophages in both in vitro and in vivo studies.
Product Specifications
CAS Number
2253123-16-7
Product Name Alternative
ABSK021, ABSK-021, CSF1R, cFms
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.80% (May vary between batches)
Solubility
DMSO:150 mg/mL (356.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.76 mM)
Smiles
O=C (NC=1N=C (C (OC2=CC=NC (=C2) C=3C=NN (C3) C) =CC1) C) N4C (=O) C (C) (C) CC4
Molecular Formula
C22H24N6O3
Molecular Weight
420.46
Storage Conditions
-20°C
Notes
For research use only.
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