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SOS1-IN-16

SOS1-IN-16 (Comp 54) is a potent and selective SOS1 inhibitor with an IC50 of 7.2 nM. It also inhibits CYP3A4 (IC50 = 8.9 μM with testosterone) . This compound is a valuable chemical probe for investigating SOS1/KRAS-dependent signaling pathways in cancer research, applicable in both cellular and biochemical studies.

Product Specifications

CAS Number

2930763-85-0

Field of Research

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Smiles

N ([C@H] (C) C1=C (F) C (C (CO) (F) F) =CC=C1) C=2C3=C (C=CC (=C3) C4=CC (CC (N (C) C) =O) =C (OC) C=C4) N=C (C) N2

Molecular Formula

C30H31F3N4O3

Molecular Weight

552.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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